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XK469

抗癌化学试剂
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三月 28, 2018
名字:XK469
描述:Description: XK489 is a synthetic quinoxaline phenoxypropionic acid derivative with proapoptotic and antiproliferative activities. R(+)XK469 selectively inhibits topoisomerase II-beta, blocks activation of MEK/MAPK signaling kinases, stimulates caspases, and upregulates p53-dependent proteins, including cyclins A and B1, thereby arresting cancer cells in the G2/M phase of the cell cycle. Both R(+) and S(-) isomers of this agent are cytotoxic, although the R-isomer is more potent.
规格:1g;2g;5g;
理论分析:THEORETICAL ANALYSIS
MedKoo Cat#: 206014
Name: XK469
CAS#: 157435-10-4 (free)
Chemical Formula: C17H13ClN2O4
Exact Mass: 344.05638
Molecular Weight: 344.74912
Elemental Analysis: C, 59.23; H, 3.80; Cl, 10.28; N, 8.13; O, 18.56
技术数据:Appearance: Solid powder Purity: >98% (or refer to the Certificate of Analysis) Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Solubility: Soluble in DMSO, not in water Shelf Life: >5 years if stored properly Drug Formulation: This drug may be formulated in DMSO Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months). Harmonized System Code: 293490
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